JCRB No. JCRB0156 Cell Name KHYG-1
Profile Human natural killer cell line with a p53 point mutation as a model for p53-associated leukemogenesis and a model for differentiation of NK/T cells. Other Name KHYG
Animal human Strain
Genus Homo Species sapiens
Sex F Age 45
Identity Tissue for Primary Cancer hemo-lymphocytic
Case history aggressive NK cell leukemia Metastasis No
Tissue Metastasized Genetics p53 point mutation and cytogenetic characteristics
Life Span infinite Crisis PDL
Morphology lymphocyte-like Character high NK/LAK activity, IFN gamma production etc.
Classify tumor Established by Yagita,M.
Registered by Yagita,M. Regulation for Distribution not defined
Comment Year 2000
Medium RPMI1640 medium containing with 10% fetal calf serum and 100 units/ml of rIL-2(Shionogi). Methods for Passages Simple dilution because of suspension cell culture. Subculture every 3-4 days with split ratio = 1/4.
Cell Number on Passage Split 1/4 every 3-4 days. Race Jpanese
CO2 Conc. 5 % Tissue Sampling peripheral blood
Tissue Type